Dr MB’s NR

£90.00

Nicotinamide Riboside

Nicotinamide Riboside is an anti-aging supplement, as it boosts your body’s levels of NAD+, which acts as fuel for many key biological processes. NR boosts levels of NAD+, which is linked to potential health benefits regarding ageing, brain health, heart disease risk and much more. . . .

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Description

Dr MB’s NR

This Nicotinamide Riboside gives 400mg per capsule.

One of the strongest in the world and the purest form of NR

What Is Nicotinamide Riboside? How Does It Work?

Nicotinamide riboside, which is also called niagen, is a form of vitamin B3. It serves as a precursor for nicotinamide adenine dinucleotide (NAD+), a coenzyme that’s needed for important body functions, like metabolism, energy production, regulating the body’s circadian rhythm and repairing DNA damage.

You may be used to seeing “niacin” as a common form of vitamin B3. Niacin is often added to packaged foods in order to reduce the risk of vitamin B3 deficiency.

Like other forms of vitamin B3, nicotinamide Riboside is converted by your body into Micotinamide Adenine Dinucleotide (NAD+), a coenzyme or helper molecule.

NAD+ acts as fuel for many key biological processes.

However, the amount of NAD+ in your body naturally falls with age. 

Low NAD+ levels have been linked to health concerns like ageing and chronic illnesses, such as diabetes, heart disease, Alzheimer’s disease and vision loss. Interestingly, research has found that raising NAD+ levels helps reverse signs of ageing and lower the risk of many chronic diseases. Nicotinamide Riboside supplements have quickly become popular because they appear to be especially effective at raising NAD+ levels.

Nicotinamide riboside is an anti-aging supplement, as it boosts your body’s levels of NAD+, which acts as fuel for many key biological processes. Nicotinamide riboside boosts levels of NAD+, which is linked to potential health benefits regarding ageing, brain health, heart disease risk and more.

As we age, our NAD+ levels naturally decline, and low levels of the coenzyme have been linked to ageing and some common health conditions, like heart disease and neurodegenerative disease.

Nicotinamide Riboside has gained attention because of its ability to raise NAD+ levels.

Potential Benefits

  • Stimulates NAD+ Metabolism
  •  Improves Exercise Performance
  • Boosts Cognitive Health
  • Reduces the Risk of Cardiovascular Disease
  • Converting food into energy
  • Repairing damaged DNA
  • Fortifying cells’ defense systems
  • Setting your body’s internal clock or circadian rhythm

SIRTUINS ACTIVATOR

Anti-ageing proteins:

They are called SIRT and they are responsible for the production of sirtuins, fundamental proteins that allow the cell to live longer. Scientists have begun to understand how to stimulate them pharmacologically but also with natural molecules.

When we are too stressed, it is often necessary to stop, take a break and regain energy. This rule applies not only to us, but also to our cells.

If they are subjected to stress our cells rest and renovate themselves. Natural evolution has selected precise mechanisms that allow cells to enter a state of “stand-by”: a recovery system that prolongs the life of the cell and also that of our organism. But how does this work?

Scientists have identified a family of genes that play a fundamental role in this system of recovery and are therefore considered the most important longevity genes. They are called SIRT genes and there are seven of them within human cells.

These seven genes are responsible for the production of sirtuins, proteins essential for the survival of all living cells and organisms. They are activated in response to threats or conditions of metabolic stress: cold, food shortages and imminent danger. In all these cases, sirtuins reduce the cell’s reproduction activity to concentrate all resources on survival.

What does all this have to do with longevity? Several studies have shown how the activity of sirtuins can slow down the ageing process and can reduce the risk of related diseases, such as cancer, metabolic and neurodegenerative diseases.

If sirtuin activity is compromised, the risk of metabolic syndrome and diabetes increases, and we become more susceptible to the negative effects of high-fat diets.

For example, it has been observed that if sirtuin activity is compromised, not only the risk of metabolic syndrome and type 2 diabetes increase, but also the other negative effects of high-fat dietary regimens are exacerbated.

In addition, scientists have highlighted how sirtuin activity is fundamental for the maintenance of cardiac health. Sirtuins also maintain proper functioning of the circadian rhythm, also known as the sleep-wake cycle, which is  highly affected by ageing. These are some of the reasons for which sirtuins have been defined as longevity proteins.

Several natural molecules have been identified which are able to activate sirtuins.

Natural molecules that has recently attracted the attention of researchers are:

NR (nicotinamide riboside),

NMN (Nicotinamide mononucleotide),

Fucoidan – Brown Algae Extract,

Sulforaphane,

Indol 3C

Spermidine & Mangiferin

Resveratrol

When these enter our cells, they turns into a molecule called NAD (nicotinamide adenin dinucleotide), which is essential for the activity of more than 500 enzymes, including sirtuins.

As we age, NAD levels diminish, which results in decreased functioning of sirtuins and many other enzymes. It has been shown, however, that dietary supplementation with the above mentioned molecules regenerates physiological NAD levels and activates sirtuins.

Sirtuin-activating compounds (STAC) are chemical compounds having an effect on sirtuins, a group of enzymes that use NAD+ to remove acetyl groups from proteins. They are caloric restriction mimetic compounds that may be helpful in treating various age related diseases.

Autophagy is an evolutionary self-preservation mechanism that allows the body to remove dysfunctional cells and recycle some of them for cell repair and irrigation. In other words, Autophagy is a method of the body that wipes out damaged cells to regenerate newer and healthier cells. The main benefit of Autophagy is anti-ageing. The cellular level removes toxic proteins, recycling residual protein, provides energy, and promotes healthy cell regeneration.